Does Ozempic (semaglutide) cause heartburn?
Though heartburn is not listed as a common side effect of Ozempic® on the drug manufacturer’s website, new or worsening heartburn can be seen with initiation of GLP-1 receptor agonist medications like Ozempic. These medications slow down digestion, which can contribute to acid reflux, in addition to other gastrointestinal symptoms such as nausea, vomiting, and constipation. In those participating in trials for Wegovy®, a medication similar to Ozempic that contains the key active ingredient semaglutide, 5% of those taking the medication reported heartburn, compared to only 3% taking a placebo. Non-pharmaceutical tips to manage heartburn associated with Ozempic include avoiding foods and beverages that trigger reflux (most commonly spicy foods, tomato-based products, chocolate, onions, garlic, citrus, and peppermint, in addition to alcohol, caffeinated beverages, and carbonated beverages), eating smaller portions, not eating close to bedtime, and quitting tobacco use.
Form Health
Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.
