Does Ozempic (semaglutide) need to be refrigerated?

Yes, Ozempic® needs to be refrigerated before it is used. If you have not yet opened your Ozempic pen, then you need to store it in the refrigerator (between 36°F to 46°F). After the first use, you can either store your pen in the refrigerator (between 36°F to 46°F) or at room temperature (between 59ºF to 86ºF) for up to 56 days. To see how long your Ozempic pen is good for before opening, check the expiration date on the packaging. When giving yourself your injection, if you find that you are experiencing discomfort, you may want to allow the pen to come to room temperature first.

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Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Ozempic® is a registered trademark of Novo Nordisk A/S.