How long does Saxenda (liraglutide) stay in your system?

Saxenda® stays in your system for about 3 days. This is based on the half-life of Saxenda, which is the time it takes for 50% of the drug to be removed. The half-life of Saxenda is 13 hours. So if you take 3 mg first thing in the morning (7 am), by the evening (8 pm) you've only got half the dose remaining in your body. That's also why Saxenda requires daily dosing to ensure Saxenda stays in your system long enough to be effective whereas other medications, such as Ozempic® and Wegovy®, are administered weekly. If you miss taking Saxenda for 3 or more days, it is recommended to restart at the lowest dose (0.6 mg) as by that time Saxenda will be out of your system. You should discuss any plans to stop taking your Saxenda prescription with your healthcare provider so they can help you to do this safely.

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Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Saxenda® is a registered trademark of Novo Nordisk A/S.