What can I eat on Zepbound (tirzepatide)?

Zepbound® is intended to be used in combination with a low calorie eating plan and increased physical activity. At this time there is no one specific dietary pattern that is recommended for weight loss. Research has shown that eating patterns that create a calorie deficit help promote successful weight loss. At Form, we do not recommend restrictive eating practices or strict diets like keto. Instead, we support you in cultivating a healthy relationship with food during your weight loss journey and finding enjoyable substitutions that allow you to achieve a calorie deficit.  

It is recommended to consume adequate protein to minimize loss of lean muscle in combination with physical activity (especially resistance training). The type of protein you eat might include lean animal protein, seafood, dairy, along with plant-based options such as soy, whole grains, and beans depending on your dietary preferences. As Zepbound can cause constipation, it can be helpful to increase your fiber intake through fruits, vegetables, beans, and whole grains. Additionally, Zepbound commonly causes heartburn so avoiding fatty/greasy foods, spicy foods, and other triggers of heartburn or acid reflux is advised. Another way Zepbound helps you lose weight is by slowing down digestion so food stays in your stomach longer and you feel fuller. When taking this medication, try serving yourself half of your normal portion and wait 10 to 15 minutes afterwards to see if you are still hungry for more. Patients who eat quickly and consume the same volume as before taking the medication may find they feel overly full and sick.

Working with a Registered Dietitian while taking Zepbound for weight loss can ensure you are following a nutritious eating plan that will support your weight loss in a way that is sustainable for long term healthy weight management. Form Health Registered Dietitians work with patients to develop personalized nutrition plans to optimize their success.