What is Mounjaro (tirzepatide) used for?

Mounjaro® is an FDA-approved medication used to treat type 2 diabetes. It is a dual GLP-1/GIP* receptor agonist which acts to stimulate the release of insulin by the pancreas which lowers blood sugar levels. It can also improve insulin sensitivity and promote weight loss. Mounjaro is not FDA-approved for weight loss, but a medication called Zepbound®, containing the same active ingredient tirzepatide, was recently approved for weight loss treatment. In clinical trials, individuals who took tirzepatide for up to a year and a half, lost an average of 26.6% of their body weight. Doctors may prescribe Mounjaro to patients without diabetes (considered off-label use) for the purpose of weight loss in combination with healthy nutrition and increased physical activity so long as it is medically appropriate.  

*glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP)

ABOUT THE AUTHOR

Lauren Lemieux, MD, FACP, ABOM diplomate

‍Dr. Lauren Lemieux completed her Internal Medicine residency and fellowship in Clinical Nutrition at UCLA. She is board certified in Internal Medicine and diplomate of the American Board of Obesity Medicine, and as a Physician Nutrition Specialist. She is also a fellow of the American College of Physicians. Dr. Lemieux is passionate about helping her patients reach their health goals using personalized nutrition, lifestyle and weight management strategies.

Doctor, healthy food, man on a computer , and smiling women sitting on counter in baggy yellow sweatshirt

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Mounjaro® and Zepbound® and their delivery device bases are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.