Does Contrave (naltrexone/bupropion) cause constipation?

Yes, a Contrave® prescription can cause constipation and approximately 20% of people taking this medication experience this side effect. Constipation can be addressed through nutritional changes such as increased fiber intake (e.g. beans, fruits, vegetables and whole grains are good sources), regular physical activity and, in some cases, over the counter fiber supplements or stool softeners may be recommended by your prescribing provider. Importantly, if it has been more than a few days since your last bowel movement, please contact your medical provider.

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Form Health

Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Contrave® is a registered trademark of Currax Pharmaceuticals, LLC.